MedBlast(0.8) Results

• Direct References
• Indirect References
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• BLASTN
• BLASTX

Direct References:

References Summary:

1. Chang CC, Lee WH, Moser H, Valle D, Gould SJ
   Isolation of the human PEX12 gene, mutated in group 3 of the peroxisome biogenesis disorders.
   Nat Genet 1997 Apr;15(4):385-8
   PMID: 9090384
2. Jungmann J, Reins HA, Lee J, Romeo A, Hassett R, Kosman D, Jentsch S
   MAC1, a nuclear regulatory protein related to Cu-dependent transcription factors is involved in Cu/Fe utilization and stress resistance in yeast.
   EMBO J 1993 Dec 15;12(13):5051-6
   PMID: 8262047
3. Vassal A, Boulet A, Decoster E, Faye G
   QRI8, a novel ubiquitin-conjugating enzyme in Saccharomyces cerevisiae.
   Biochim Biophys Acta 1992 Sep 24;1132(2):211-3
   PMID: 1327148
4. Joets J, Pousset D, Marcireau C, Karst F
   Characterization of the Saccharomyces cerevisiae FMS1 gene related to Candida albicans corticosteroid-binding protein 1.
   Curr Genet 1996 Jul 31;30(2):115-20
   PMID: 8660467
5. Horn N, Swindell S, Dodd H, Gasson M
   Nisin biosynthesis genes are encoded by a novel conjugative transposon.
   Mol Gen Genet 1991 Aug;228(1-2):129-35
   PMID: 1679523

Indirect References:

References Summary:

1. Yamaguchi-Iwai Y, Serpe M, Haile D, Yang W, Kosman DJ, Klausner RD, Dancis A
   Homeostatic regulation of copper uptake in yeast via direct binding of MAC1 protein to upstream regulatory sequences of FRE1 and CTR1.
   J Biol Chem 1997 Jul 11;272(28):17711-8
   PMID: 9211922
2. Keller G, Gross C, Kelleher M, Winge DR
   Functional independence of the two cysteine-rich activation domains in the yeast Mac1 transcription factor.
   J Biol Chem 2000 Sep 22;275(38):29193-9
   PMID: 10887177
3. Serpe M, Joshi A, Kosman DJ
   Structure-function analysis of the protein-binding domains of Mac1p, a copper-dependent transcriptional activator of copper uptake in Saccharomyces cerevisiae.
   J Biol Chem 1999 Oct 8;274(41):29211-9
   PMID: 10506178
4. Brown KR, Keller GL, Pickering IJ, Harris HH, George GN, Winge DR
   Structures of the cuprous-thiolate clusters of the Mac1 and Ace1 transcriptional activators.
   Biochemistry 2002 May 21;41(20):6469-76
   PMID: 12009910
5. Jensen LT, Posewitz MC, Srinivasan C, Winge DR
   Mapping of the DNA binding domain of the copper-responsive transcription factor Mac1 from Saccharomyces cerevisiae.
   J Biol Chem 1998 Sep 11;273(37):23805-11
   PMID: 9726991
6. Georgatsou E, Mavrogiannis LA, Fragiadakis GS, Alexandraki D
   The yeast Fre1p/Fre2p cupric reductases facilitate copper uptake and are regulated by the copper-modulated Mac1p activator.
   J Biol Chem 1997 May 23;272(21):13786-92
   PMID: 9153234
7. Martins LJ, Jensen LT, Simon JR, Keller GL, Winge DR, Simons JR
   Metalloregulation of FRE1 and FRE2 homologs in Saccharomyces cerevisiae.
   J Biol Chem 1998 Sep 11;273(37):23716-21
   PMID: 9726978
8. Beaudoin J, Mercier A, Langlois R, Labbe S
   The Schizosaccharomyces pombe Cuf1 is composed of functional modules from two distinct classes of copper metalloregulatory transcription factors.
   J Biol Chem 2003 Feb 10;
   PMID: 12578838
9. Voutsina A, Fragiadakis GS, Boutla A, Alexandraki D
   The second cysteine-rich domain of Mac1p is a potent transactivator that modulates DNA binding efficiency and functionality of the protein.
   FEBS Lett 2001 Apr 6;494(1-2):38-43
   PMID: 11297731
10. Georgatsou E, Alexandraki D
    Regulated expression of the Saccharomyces cerevisiae Fre1p/Fre2p Fe/Cu reductase related genes.
    Yeast 1999 May;15(7):573-84
    PMID: 10341420
11. Osiewacz HD, Nuber U
    GRISEA, a putative copper-activated transcription factor from Podospora anserina involved in differentiation and senescence.
    Mol Gen Genet 1996 Aug 27;252(1-2):115-24
    PMID: 8804410
12. Beaudoin J, Labbe S
    The fission yeast copper-sensing transcription factor Cuf1 regulates the copper transporter gene expression through an Ace1/Amt1-like recognition sequence.
    J Biol Chem 2001 May 4;276(18):15472-80
    PMID: 11278870
13. Graden JA, Winge DR
    Copper-mediated repression of the activation domain in the yeast Mac1p transcription factor.
    Proc Natl Acad Sci U S A 1997 May 27;94(11):5550-5
    PMID: 9159110
14. Zhu Z, Labbe S, Pena MM, Thiele DJ
    Copper differentially regulates the activity and degradation of yeast Mac1 transcription factor.
    J Biol Chem 1998 Jan 16;273(3):1277-80
    PMID: 9430656
15. Angrave FE, Avery SV
    Antioxidant functions required for insusceptibility of Saccharomyces cerevisiae to tetracycline antibiotics.
    Antimicrob Agents Chemother 2001 Oct;45(10):2939-42
    PMID: 11557497
16. Joshi A, Serpe M, Kosman DJ
    Evidence for (Mac1p)2.DNA ternary complex formation in Mac1p-dependent transactivation at the CTR1 promoter.
    J Biol Chem 1999 Jan 1;274(1):218-26
    PMID: 9867833
17. Jensen LT, Winge DR
    Identification of a copper-induced intramolecular interaction in the transcription factor Mac1 from Saccharomyces cerevisiae.
    EMBO J 1998 Sep 15;17(18):5400-8
    PMID: 9736617
18. Winge DR
    Copper-regulatory domain involved in gene expression.
    Prog Nucleic Acid Res Mol Biol 1998;58:165-95
    PMID: 9308366
19. Nitiss JL
    A copper connection to the uptake of platinum anticancer drugs.
    Proc Natl Acad Sci U S A 2002 Oct 29;99(22):13963-5
    PMID: 12391309
20. Yonkovich J, McKenndry R, Shi X, Zhu Z
    Copper ion-sensing transcription factor Mac1p post-translationally controls the degradation of its target gene product Ctr1p.
    J Biol Chem 2002 Jul 5;277(27):23981-4
    PMID: 12011036
21. Jamison McDaniels CP, Jensen LT, Srinivasan C, Winge DR, Tullius TD
    The yeast transcription factor Mac1 binds to DNA in a modular fashion.
    J Biol Chem 1999 Sep 17;274(38):26962-7
    PMID: 10480908
22. Borghouts C, Osiewacz HD
    GRISEA, a copper-modulated transcription factor from Podospora anserina involved in senescence and morphogenesis, is an ortholog of MAC1 in Saccharomyces cerevisiae.
    Mol Gen Genet 1998 Dec;260(5):492-502
    PMID: 9894921
23. Hassett R, Kosman DJ
    Evidence for Cu(II) reduction as a component of copper uptake by Saccharomyces cerevisiae.
    J Biol Chem 1995 Jan 6;270(1):128-34
    PMID: 7814363
24. Gross C, Kelleher M, Iyer VR, Brown PO, Winge DR
    Identification of the copper regulon in Saccharomyces cerevisiae by DNA microarrays.
    J Biol Chem 2000 Oct 13;275(41):32310-6
    PMID: 10922376
25. Labbe S, Zhu Z, Thiele DJ
    Copper-specific transcriptional repression of yeast genes encoding critical components in the copper transport pathway.
    J Biol Chem 1997 Jun 20;272(25):15951-8
    PMID: 9188496
26. Dancis A
    Genetic analysis of iron uptake in the yeast Saccharomyces cerevisiae.
    J Pediatr 1998 Mar;132(3 Pt 2):S24-9
    PMID: 9546033
27. Pena MM, Koch KA, Thiele DJ
    Dynamic regulation of copper uptake and detoxification genes in Saccharomyces cerevisiae.
    Mol Cell Biol 1998 May;18(5):2514-23
    PMID: 9599102
28. Hassett R, Dix DR, Eide DJ, Kosman DJ
    The Fe(II) permease Fet4p functions as a low affinity copper transporter and supports normal copper trafficking in Saccharomyces cerevisiae.
    Biochem J 2000 Oct 15;351 Pt 2:477-84
    PMID: 11023834
29. Pena MMO, Koch KA, Thiele DJ
    Dynamic regulation of copper uptake and detoxification genes in saccharomyces cerevisiae
    Mol Cell Biol 1998 Jun;18(6):2514-23
    PMID: 9573314
30. Lesuisse E, Simon-Casteras M, Labbe P
    Siderophore-mediated iron uptake in Saccharomyces cerevisiae: the SIT1 gene encodes a ferrioxamine B permease that belongs to the major facilitator superfamily.
    Microbiology 1998 Dec;144 ( Pt 12):3455-62
    PMID: 9884238

Options:

• Limit of E-value: 1e-20
• Limit of Length: 100000
• Limit of references returned each search: 40
• Limit of retry times: 3
• Direct references: Yes
• Indirect references: Yes
• Allow symbol with hyphen: Yes
• Use stop word list: Yes
• Thesaurus:
  • Saccharomyces cerevisiae (Version: 20021123.0)

 
BLASTN 2.2.5 [Nov-16-2002]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.
RID: 1048225145-06615-18542
Query= 
         (1254 letters)

Database: All GenBank+EMBL+DDBJ+PDB sequences (but no EST, STS, GSS,
or phase 0, 1 or 2 HTGS sequences) 
           1,706,607 sequences; 7,920,131,457 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|798922|emb|Z49211.1|SC9711X S.cerevisiae chromosome XIII cosm...  2444   0.0  
gi|406766|emb|X74551.1|SCMAC1 S.cerevisiae gene for MAC1 metal b...  2428   0.0  
gi|4256|emb|X66829.1|SCQRI8G S.cerevisiae QRI8 gene for ubiquiti...   406   e-110
gi|1143555|emb|X81848.1|SCFMS1 S.cerevisiae FMS1 gene                 163   8e-37
gi|3970796|emb|Y13766.1|SAPNPA Staphylococcus aureus pnpA gene         44   0.51 
gi|16751484|dbj|AP001877.4| Homo sapiens genomic DNA, chromosome...    44   0.51 
gi|14517576|dbj|AP000870.4| Homo sapiens genomic DNA, chromosome...    44   0.51 
gi|14245743|dbj|AP000627.4| Homo sapiens genomic DNA, chromosome...    44   0.51 
gi|28626592|gb|AC139337.5| Homo sapiens 3 BAC RP11-301H7 (Roswel...    42   2.0  
gi|27597023|gb|AC132220.10| Homo sapiens chromosome 15, clone RP...    42   2.0  
gi|26245913|gb|AC134661.4| Homo sapiens chromosome 15, clone CTD...    42   2.0  
gi|24462388|gb|AC135321.2| Homo sapiens chromosome 3 clone RP11-...    42   2.0  
gi|21313971|gb|AC111193.5| Homo sapiens BAC clone RP11-397D21 fr...    42   2.0  
gi|18997369|gb|AC099783.2| Homo sapiens chromosome 3 clone RP11-...    42   2.0  
gi|16418182|gb|AC092044.2| Homo sapiens chromosome 3 clone RP11-...    42   2.0  
gi|13366278|emb|AL049709.18|HSDJ18C9 Human DNA sequence from clo...    42   2.0  
gi|8698757|gb|AC022308.17|AC022308 Homo sapiens chromosome 15 cl...    42   2.0  
gi|12655312|emb|AL445123.11| Human DNA sequence from clone RP11-...    42   2.0  
gi|16555469|emb|AL390246.17| Human DNA sequence from clone RP11-...    42   2.0  
gi|13537561|dbj|AP003353.2| Homo sapiens genomic DNA, chromosome...    42   2.0  
gi|18860922|ref|NG_000002.1| Homo sapiens immunoglobulin lambda ...    40   8.0  
gi|21591803|gb|AC117381.5| Homo sapiens 3 BAC RP11-783D3 (Roswel...    40   8.0  
gi|24655780|ref|NM_139423.1| Drosophila melanogaster CG5690-PA (...    40   8.0  
gi|23092818|gb|AE003473.2| Drosophila melanogaster chromosome 3L...    40   8.0  
gi|28144465|gb|AC127277.2| Mus musculus chromosome 3 clone RP24-...    40   8.0  
gi|24270677|gb|AC026199.5| Homo sapiens chromosome 3 clone RP11-...    40   8.0  
gi|24270668|gb|AC066585.6| Homo sapiens chromosome 3 clone RP11-...    40   8.0  
gi|23496259|gb|AE014841.1| Plasmodium falciparum 3D7 chromosome ...    40   8.0  
gi|21490079|gb|AC108734.10| Homo sapiens 3 BAC RP11-259P15 (Rosw...    40   8.0  
gi|22549867|gb|AC100821.2| Homo sapiens chromosome 8, clone RP11...    40   8.0  
gi|22382034|gb|AC060764.13| Homo sapiens chromosome 8, clone RP1...    40   8.0  
gi|14336745|gb|AE006467.1| Homo sapiens 16p13.3 sequence section...    40   8.0  
gi|21539149|gb|AC010063.7| Drosophila melanogaster 3L BAC RP98-1...    40   8.0  
gi|19424444|gb|AC093180.12| Oryza sativa chromosome 3 BAC OJ1004...    40   8.0  
gi|16445200|gb|AC096736.3| Homo sapiens BAC clone RP11-171N4 fro...    40   8.0  
gi|15292546|gb|AY052118.1| Drosophila melanogaster SD06673 full ...    40   8.0  
gi|1122811|emb|Z68217.1|CEF58G6 Caenorhabditis elegans cosmid F5...    40   8.0  
gi|23894970|emb|AL772352.7| Mouse DNA sequence from clone RP23-1...    40   8.0  
gi|24474462|emb|AL713972.11| Mouse DNA sequence from clone RP23-...    40   8.0  
gi|11323377|gb|AC069247.5|AC069247 Homo sapiens chromosome 3 clo...    40   8.0  
gi|13937407|emb|AL031719.12|HS380F5 Human DNA sequence from clon...    40   8.0  
gi|16304960|emb|AL590086.4| Human DNA sequence from clone RP11-6...    40   8.0  
gi|3818397|gb|AC002308.1|AC002308 Homo sapiens Chromosome 22q11....    40   8.0  
gi|11414464|emb|AL138919.12| Human DNA sequence from clone RP3-4...    40   8.0  
gi|18077706|emb|AL606517.14| Human DNA sequence from clone RP11-...    40   8.0  
gi|6478942|gb|AC012331.9|AC012331 Homo sapiens, complete sequence      40   8.0  
gi|26082020|dbj|AK030853.1| Mus musculus adult male thymus cDNA,...    40   8.0  
gi|3560254|emb|AL031535.1|SPCC16C4 S.pombe chromosome III cosmid...    40   8.0  
gi|18307724|dbj|AP001324.4| Homo sapiens genomic DNA, chromosome...    40   8.0  
gi|2114216|dbj|D86994.1| Homo sapiens immunoglobulin lambda gene...    40   8.0  
gi|6253395|dbj|D87015.2| Homo sapiens immunoglobulin lambda gene...    40   8.0  
gi|10038693|dbj|AP001118.1| Buchnera sp. APS genomic DNA, comple...    40   8.0  

ALIGNMENTS
>gi|798922|emb|Z49211.1|SC9711X S.cerevisiae chromosome XIII cosmid 9711
          Length = 30011

 Score = 2444 bits (1233), Expect = 0.0
 Identities = 1247/1254 (99%)
 Strand = Plus / Minus

                                                                         
Query: 1     atgataatatttaatgggaacaaatatgcgtgtgcatcgtgcatcagagggcatcgctct 60
             ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 20704 atgataatatttaatgggaacaaatatgcgtgtgcatcgtgcatcagagggcatcgctct 20645

                                                                         
Query: 61    tcaacatgcaggcattctcaccgaatgctaattaaggtgagaactagaggaagaccttca 120
             ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 20644 tcaacatgcaggcattctcaccgaatgctaattaaggtgagaactagaggaagaccttca 20585

                                                                         
Query: 121   cccatggctatcagagacgctattttagtagactctacatcgcaaagtacagaatacgaa 180
             ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 20584 cccatggctatcagagacgctattttagtagactctacatcgcaaagtacagaatacgaa 20525

                                                                         
Query: 181   aatggtgcacaaattgaaggtgactgctgcagcgcaatgaatcaacagccaatactgttt 240
             ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 20524 aatggtgcacaaattgaaggtgactgctgcagcgcaatgaatcaacagccaatactgttt 20465

                                                                         
Query: 241   gtacgtgcctctgctgttagaaaggcaagaatgataaacggaaaattgcatatattaatg 300
             ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 20464 gtacgtgcctctgctgttagaaaggcaagaatgataaacggaaaattgcatatattaatg 20405

                                                                         
Query: 301   gaggaaggtttcactgctcatgagcctaaagatattagcacatttaccgatgatggtaac 360
             ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 20404 gaggaaggtttcactgctcatgagcctaaagatattagcacatttaccgatgatggtaac 20345

                                                                         
Query: 361   aaatatatcaccgaaacggagtttcttaggaaacactctcccaaagctccggcaacagga 420
             ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 20344 aaatatatcaccgaaacggagtttcttaggaaacactctcccaaagctccggcaacagga 20285

                                                                         
Query: 421   acaatatctccggactctaccaagtcatcttcttcaagtgagaagaaagagcgaagccgg 480
             ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 20284 acaatatctccggactctaccaagtcatcttcttcaagtgagaagaaagagcgaagccgg 20225

                                                                         
Query: 481   cttcaacaggagcctatacgacatttttcaaactgctgtaagaaagataaatcacagaac 540
             ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 20224 cttcaacaggagcctatacgacatttttcaaactgctgtaagaaagataaatcacagaac 20165

                                                                         
Query: 541   ccagcttctaatggcaagacgaacaaggcaccgtctgatgacatatttacgccatacggc 600
             ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 20164 ccagcttctaatggcaagacgaacaaggcaccgtctgatgacatatttacgccatacggc 20105

                                                                         
Query: 601   tccttggaatctacgtccgcttttaacgatattttacaagaaaactacaatagttctgtt 660
             ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 20104 tccttggaatctacgtccgcttttaacgatattttacaagaaaactacaatagttctgtt 20045

                                                                         
Query: 661   cctggtgcgcatgacagttcagaaacactcaccccacaaagtacaacaacgattgctgct 720
             ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 20044 cctggtgcgcatgacagttcagaaacactcaccccacaaagtacaacaacgattgctgct 19985

                                                                         
Query: 721   cctcattcaagcgacgttgcttcgaaagttgaagtcctgactcataagggcannnnnnna 780
             ||||||||||||||||||||||||||||||||||||||||||||||||||||       |
Sbjct: 19984 cctcattcaagcgacgttgcttcgaaagttgaagtcctgactcataagggcattttttta 19925

                                                                         
Query: 781   agcacgcagtgctcttgtgaagatgaaagctgcccatgtgttaattgtctaatccataga 840
             ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 19924 agcacgcagtgctcttgtgaagatgaaagctgcccatgtgttaattgtctaatccataga 19865

                                                                         
Query: 841   agcgaagaggaactgaattcttatattcaacaaagtggtgttcctttaaccaatattggt 900
             ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 19864 agcgaagaggaactgaattcttatattcaacaaagtggtgttcctttaaccaatattggt 19805

                                                                         
Query: 901   gaagctcaaattactgataagatgatggattatttggatgattgtaaatgcactgacaag 960
             ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 19804 gaagctcaaattactgataagatgatggattatttggatgattgtaaatgcactgacaag 19745

                                                                         
Query: 961   gaatgcatatgtcctccggataactgcacttgtgatggatgtttttctcactctacaaat 1020
             ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 19744 gaatgcatatgtcctccggataactgcacttgtgatggatgtttttctcactctacaaat 19685

                                                                         
Query: 1021  ataattccatttgaaaaattctttttctatggaattctgaatgcaagattaacaaggaaa 1080
             ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 19684 ataattccatttgaaaaattctttttctatggaattctgaatgcaagattaacaaggaaa 19625

                                                                         
Query: 1081  actcaaataaaattcaaaggtaaattggtgccgtcaaaatattggtgggattttttgaag 1140
             ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 19624 actcaaataaaattcaaaggtaaattggtgccgtcaaaatattggtgggattttttgaag 19565

                                                                         
Query: 1141  ttgcaagtgccattgatgacagatgctcagttagaattacttgacattcatgcgtggttt 1200
             ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 19564 ttgcaagtgccattgatgacagatgctcagttagaattacttgacattcatgcgtggttt 19505

                                                                   
Query: 1201  caaaaattagtctctaattatgcaccacatctaagcgatgccaccacttcataa 1254
             ||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 19504 caaaaattagtctctaattatgcaccacatctaagcgatgccaccacttcataa 19451


>gi|406766|emb|X74551.1|SCMAC1 S.cerevisiae gene for MAC1 metal binding activator
          Length = 1701

 Score = 2428 bits (1225), Expect = 0.0
 Identities = 1245/1254 (99%)
 Strand = Plus / Plus

                                                                        
Query: 1    atgataatatttaatgggaacaaatatgcgtgtgcatcgtgcatcagagggcatcgctct 60
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 142  atgataatatttaatgggaacaaatatgcgtgtgcatcgtgcatcagagggcatcgctct 201

                                                                        
Query: 61   tcaacatgcaggcattctcaccgaatgctaattaaggtgagaactagaggaagaccttca 120
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 202  tcaacatgcaggcattctcaccgaatgctaattaaggtgagaactagaggaagaccttca 261

                                                                        
Query: 121  cccatggctatcagagacgctattttagtagactctacatcgcaaagtacagaatacgaa 180
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 262  cccatggctatcagagacgctattttagtagactctacatcgcaaagtacagaatacgaa 321

                                                                        
Query: 181  aatggtgcacaaattgaaggtgactgctgcagcgcaatgaatcaacagccaatactgttt 240
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 322  aatggtgcacaaattgaaggtgactgctgcagcgcaatgaatcaacagccaatactgttt 381

                                                                        
Query: 241  gtacgtgcctctgctgttagaaaggcaagaatgataaacggaaaattgcatatattaatg 300
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 382  gtacgtgcctctgctgttagaaaggcaagaatgataaacggaaaattgcatatattaatg 441

                                                                        
Query: 301  gaggaaggtttcactgctcatgagcctaaagatattagcacatttaccgatgatggtaac 360
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 442  gaggaaggtttcactgctcatgagcctaaagatattagcacatttaccgatgatggtaac 501

                                                                        
Query: 361  aaatatatcaccgaaacggagtttcttaggaaacactctcccaaagctccggcaacagga 420
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 502  aaatatatcaccgaaacggagtttcttaggaaacactctcccaaagctccggcaacagga 561

                                                                        
Query: 421  acaatatctccggactctaccaagtcatcttcttcaagtgagaagaaagagcgaagccgg 480
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 562  acaatatctccggactctaccaagtcatcttcttcaagtgagaagaaagagcgaagccgg 621

                                                                        
Query: 481  cttcaacaggagcctatacgacatttttcaaactgctgtaagaaagataaatcacagaac 540
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 622  cttcaacaggagcctatacgacatttttcaaactgctgtaagaaagataaatcacagaac 681

                                                                        
Query: 541  ccagcttctaatggcaagacgaacaaggcaccgtctgatgacatatttacgccatacggc 600
            ||||||||||||||||||||||||||||||||||||||||||||||||||  ||||||||
Sbjct: 682  ccagcttctaatggcaagacgaacaaggcaccgtctgatgacatatttaccgcatacggc 741

                                                                        
Query: 601  tccttggaatctacgtccgcttttaacgatattttacaagaaaactacaatagttctgtt 660
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 742  tccttggaatctacgtccgcttttaacgatattttacaagaaaactacaatagttctgtt 801

                                                                        
Query: 661  cctggtgcgcatgacagttcagaaacactcaccccacaaagtacaacaacgattgctgct 720
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 802  cctggtgcgcatgacagttcagaaacactcaccccacaaagtacaacaacgattgctgct 861

                                                                        
Query: 721  cctcattcaagcgacgttgcttcgaaagttgaagtcctgactcataagggcannnnnnna 780
            ||||||||||||||||||||||||||||||||||||||||||||||||||||       |
Sbjct: 862  cctcattcaagcgacgttgcttcgaaagttgaagtcctgactcataagggcattttttta 921

                                                                        
Query: 781  agcacgcagtgctcttgtgaagatgaaagctgcccatgtgttaattgtctaatccataga 840
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 922  agcacgcagtgctcttgtgaagatgaaagctgcccatgtgttaattgtctaatccataga 981

                                                                        
Query: 841  agcgaagaggaactgaattcttatattcaacaaagtggtgttcctttaaccaatattggt 900
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 982  agcgaagaggaactgaattcttatattcaacaaagtggtgttcctttaaccaatattggt 1041

                                                                        
Query: 901  gaagctcaaattactgataagatgatggattatttggatgattgtaaatgcactgacaag 960
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 1042 gaagctcaaattactgataagatgatggattatttggatgattgtaaatgcactgacaag 1101

                                                                        
Query: 961  gaatgcatatgtcctccggataactgcacttgtgatggatgtttttctcactctacaaat 1020
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 1102 gaatgcatatgtcctccggataactgcacttgtgatggatgtttttctcactctacaaat 1161

                                                                        
Query: 1021 ataattccatttgaaaaattctttttctatggaattctgaatgcaagattaacaaggaaa 1080
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 1162 ataattccatttgaaaaattctttttctatggaattctgaatgcaagattaacaaggaaa 1221

                                                                        
Query: 1081 actcaaataaaattcaaaggtaaattggtgccgtcaaaatattggtgggattttttgaag 1140
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 1222 actcaaataaaattcaaaggtaaattggtgccgtcaaaatattggtgggattttttgaag 1281

                                                                        
Query: 1141 ttgcaagtgccattgatgacagatgctcagttagaattacttgacattcatgcgtggttt 1200
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 1282 ttgcaagtgccattgatgacagatgctcagttagaattacttgacattcatgcgtggttt 1341

                                                                  
Query: 1201 caaaaattagtctctaattatgcaccacatctaagcgatgccaccacttcataa 1254
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 1342 caaaaattagtctctaattatgcaccacatctaagcgatgccaccacttcataa 1395


>gi|4256|emb|X66829.1|SCQRI8G S.cerevisiae QRI8 gene for ubiquitin-conjugating enzyme
          Length = 1139

 Score =  406 bits (205), Expect = e-110
 Identities = 212/213 (99%), Gaps = 1/213 (0%)
 Strand = Plus / Minus

                                                                       
Query: 1   atgataatatttaatgggaacaaatatgcgtgtgcatcgtgcatcagagggcatcgctct 60
           ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 213 atgataatatttaatgggaacaaatatgcgtgtgcatcgtgcatcagagggcatcgctct 154

                                                                       
Query: 61  tcaacatgcaggcattctca-ccgaatgctaattaaggtgagaactagaggaagaccttc 119
           |||||||||||||||||||| |||||||||||||||||||||||||||||||||||||||
Sbjct: 153 tcaacatgcaggcattctcaaccgaatgctaattaaggtgagaactagaggaagaccttc 94

                                                                       
Query: 120 acccatggctatcagagacgctattttagtagactctacatcgcaaagtacagaatacga 179
           ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 93  acccatggctatcagagacgctattttagtagactctacatcgcaaagtacagaatacga 34

                                            
Query: 180 aaatggtgcacaaattgaaggtgactgctgcag 212
           |||||||||||||||||||||||||||||||||
Sbjct: 33  aaatggtgcacaaattgaaggtgactgctgcag 1


>gi|1143555|emb|X81848.1|SCFMS1 S.cerevisiae FMS1 gene
          Length = 2040

 Score =  163 bits (82), Expect = 8e-37
 Identities = 82/82 (100%)
 Strand = Plus / Minus

                                                                        
Query: 1173 agaattacttgacattcatgcgtggtttcaaaaattagtctctaattatgcaccacatct 1232
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 2040 agaattacttgacattcatgcgtggtttcaaaaattagtctctaattatgcaccacatct 1981

                                  
Query: 1233 aagcgatgccaccacttcataa 1254
            ||||||||||||||||||||||
Sbjct: 1980 aagcgatgccaccacttcataa 1959


>gi|3970796|emb|Y13766.1|SAPNPA Staphylococcus aureus pnpA gene
          Length = 1094

 Score = 44.1 bits (22), Expect = 0.51
 Identities = 22/22 (100%)
 Strand = Plus / Plus

                                 
Query: 703 acaacaacgattgctgctcctc 724
           ||||||||||||||||||||||
Sbjct: 567 acaacaacgattgctgctcctc 588


>gi|16751484|dbj|AP001877.4| Homo sapiens genomic DNA, chromosome 11q clone:CTD-2564P9, complete
              sequence
          Length = 167303

 Score = 44.1 bits (22), Expect = 0.51
 Identities = 25/26 (96%)
 Strand = Plus / Plus

                                        
Query: 1014   tacaaatataattccatttgaaaaat 1039
              |||||||||||||||| |||||||||
Sbjct: 162725 tacaaatataattccacttgaaaaat 162750


>gi|14517576|dbj|AP000870.4| Homo sapiens genomic DNA, chromosome 11q, clone:RP11-697H10, complete
             sequence
          Length = 179335

 Score = 44.1 bits (22), Expect = 0.51
 Identities = 25/26 (96%)
 Strand = Plus / Plus

                                       
Query: 1014  tacaaatataattccatttgaaaaat 1039
             |||||||||||||||| |||||||||
Sbjct: 15603 tacaaatataattccacttgaaaaat 15628


>gi|14245743|dbj|AP000627.4| Homo sapiens genomic DNA, chromosome 11q clone:CMB9-9I16, complete
             sequence
          Length = 120240

 Score = 44.1 bits (22), Expect = 0.51
 Identities = 25/26 (96%)
 Strand = Plus / Plus

                                       
Query: 1014  tacaaatataattccatttgaaaaat 1039
             |||||||||||||||| |||||||||
Sbjct: 92184 tacaaatataattccacttgaaaaat 92209


>gi|28626592|gb|AC139337.5| Homo sapiens 3 BAC RP11-301H7 (Roswell Park Cancer Institute Human BAC
              Library) complete sequence
          Length = 142201

 Score = 42.1 bits (21), Expect = 2.0
 Identities = 24/25 (96%)
 Strand = Plus / Minus

                                       
Query: 1074   aaggaaaactcaaataaaattcaaa 1098
              |||||||||| ||||||||||||||
Sbjct: 103387 aaggaaaacttaaataaaattcaaa 103363


>gi|27597023|gb|AC132220.10| Homo sapiens chromosome 15, clone RP11-1142D4, complete sequence
          Length = 162101

 Score = 42.1 bits (21), Expect = 2.0
 Identities = 21/21 (100%)
 Strand = Plus / Minus

                                   
Query: 521    agaaagataaatcacagaacc 541
              |||||||||||||||||||||
Sbjct: 133157 agaaagataaatcacagaacc 133137


>gi|26245913|gb|AC134661.4| Homo sapiens chromosome 15, clone CTD-3098H5, complete sequence
          Length = 63244

 Score = 42.1 bits (21), Expect = 2.0
 Identities = 21/21 (100%)
 Strand = Plus / Plus

                                  
Query: 521   agaaagataaatcacagaacc 541
             |||||||||||||||||||||
Sbjct: 33666 agaaagataaatcacagaacc 33686


>gi|24462388|gb|AC135321.2| Homo sapiens chromosome 3 clone RP11-733F11, complete sequence
          Length = 177164

 Score = 42.1 bits (21), Expect = 2.0
 Identities = 21/21 (100%)
 Strand = Plus / Plus

                                  
Query: 1085  aaataaaattcaaaggtaaat 1105
             |||||||||||||||||||||
Sbjct: 75821 aaataaaattcaaaggtaaat 75841


>gi|21313971|gb|AC111193.5| Homo sapiens BAC clone RP11-397D21 from 4, complete sequence
          Length = 73175

 Score = 42.1 bits (21), Expect = 2.0
 Identities = 21/21 (100%)
 Strand = Plus / Minus

                                 
Query: 1084 caaataaaattcaaaggtaaa 1104
            |||||||||||||||||||||
Sbjct: 4328 caaataaaattcaaaggtaaa 4308


>gi|18997369|gb|AC099783.2| Homo sapiens chromosome 3 clone RP11-115I24, complete sequence
          Length = 159870

 Score = 42.1 bits (21), Expect = 2.0
 Identities = 21/21 (100%)
 Strand = Plus / Minus

                                  
Query: 1085  aaataaaattcaaaggtaaat 1105
             |||||||||||||||||||||
Sbjct: 32693 aaataaaattcaaaggtaaat 32673


>gi|16418182|gb|AC092044.2| Homo sapiens chromosome 3 clone RP11-146E16, complete sequence
          Length = 73569

 Score = 42.1 bits (21), Expect = 2.0
 Identities = 21/21 (100%)
 Strand = Plus / Minus

                                  
Query: 1085  aaataaaattcaaaggtaaat 1105
             |||||||||||||||||||||
Sbjct: 32693 aaataaaattcaaaggtaaat 32673


>gi|13366278|emb|AL049709.18|HSDJ18C9 Human DNA sequence from clone RP1-18C9 on chromosome 20 Contains part of
              a novel gene similar to acetyl-coenzyme A synthetase, a
              novel gene similar to Gamma-glutamyltranspeptidase, a gene
              similar to HMG2a (high mobility group protein 2A), the 5'
              end of the AIB3 gene for thyroid hormone receptor binding
              protein (KIAA0181),  ESTs, STSs, GSSs, CpG Islands and the
              D20S101 marker, complete sequence
          Length = 126755

 Score = 42.1 bits (21), Expect = 2.0
 Identities = 21/21 (100%)
 Strand = Plus / Minus

                                   
Query: 1195   tggtttcaaaaattagtctct 1215
              |||||||||||||||||||||
Sbjct: 100152 tggtttcaaaaattagtctct 100132


>gi|8698757|gb|AC022308.17|AC022308 Homo sapiens chromosome 15 clone RP11-34L4, complete sequence
          Length = 166226

 Score = 42.1 bits (21), Expect = 2.0
 Identities = 21/21 (100%)
 Strand = Plus / Minus

                                  
Query: 521   agaaagataaatcacagaacc 541
             |||||||||||||||||||||
Sbjct: 16043 agaaagataaatcacagaacc 16023


>gi|12655312|emb|AL445123.11| Human DNA sequence from clone RP11-242F11 on chromosome 6, complete
              sequence
          Length = 120709

 Score = 42.1 bits (21), Expect = 2.0
 Identities = 24/25 (96%)
 Strand = Plus / Minus

                                       
Query: 1068   attaacaaggaaaactcaaataaaa 1092
              ||||||||| |||||||||||||||
Sbjct: 110758 attaacaagtaaaactcaaataaaa 110734


>gi|16555469|emb|AL390246.17| Human DNA sequence from clone RP11-490C5 on chromosome 9, complete
             sequence
          Length = 103750

 Score = 42.1 bits (21), Expect = 2.0
 Identities = 21/21 (100%)
 Strand = Plus / Minus

                                  
Query: 519   taagaaagataaatcacagaa 539
             |||||||||||||||||||||
Sbjct: 91236 taagaaagataaatcacagaa 91216


>gi|13537561|dbj|AP003353.2| Homo sapiens genomic DNA, chromosome 8q23, clone: KB1491A8
          Length = 159490

 Score = 42.1 bits (21), Expect = 2.0
 Identities = 21/21 (100%)
 Strand = Plus / Minus

                                   
Query: 1074   aaggaaaactcaaataaaatt 1094
              |||||||||||||||||||||
Sbjct: 135145 aaggaaaactcaaataaaatt 135125


>gi|18860922|ref|NG_000002.1| Homo sapiens immunoglobulin lambda locus (IGL@) on chromosome 22
          Length = 909203

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Minus

                                  
Query: 519    taagaaagataaatcacaga 538
              ||||||||||||||||||||
Sbjct: 637959 taagaaagataaatcacaga 637940



 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Minus

                                  
Query: 519    taagaaagataaatcacaga 538
              ||||||||||||||||||||
Sbjct: 703547 taagaaagataaatcacaga 703528


>gi|21591803|gb|AC117381.5| Homo sapiens 3 BAC RP11-783D3 (Roswell Park Cancer Institute Human BAC
              Library) complete sequence
          Length = 205933

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Plus

                                  
Query: 670    catgacagttcagaaacact 689
              ||||||||||||||||||||
Sbjct: 183245 catgacagttcagaaacact 183264


>gi|24655780|ref|NM_139423.1| Drosophila melanogaster CG5690-PA (CG5690), mRNA
          Length = 2222

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Plus

                                
Query: 1042 tttttctatggaattctgaa 1061
            ||||||||||||||||||||
Sbjct: 2179 tttttctatggaattctgaa 2198


>gi|23092818|gb|AE003473.2| Drosophila melanogaster chromosome 3L, section 7 of 83 of the complete
              sequence
          Length = 308108

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Plus

                                  
Query: 1042   tttttctatggaattctgaa 1061
              ||||||||||||||||||||
Sbjct: 112393 tttttctatggaattctgaa 112412


>gi|28144465|gb|AC127277.2| Mus musculus chromosome 3 clone RP24-221P14, complete sequence
          Length = 159339

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 23/24 (95%)
 Strand = Plus / Minus

                                     
Query: 1086  aataaaattcaaaggtaaattggt 1109
             ||||||||||| ||||||||||||
Sbjct: 15432 aataaaattcataggtaaattggt 15409


>gi|24270677|gb|AC026199.5| Homo sapiens chromosome 3 clone RP11-507D6 map 3p, complete sequence
          Length = 201531

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Plus

                                
Query: 193  attgaaggtgactgctgcag 212
            ||||||||||||||||||||
Sbjct: 2305 attgaaggtgactgctgcag 2324


>gi|24270668|gb|AC066585.6| Homo sapiens chromosome 3 clone RP11-24B16 map 3p, complete sequence
          Length = 134862

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Minus

                                 
Query: 193   attgaaggtgactgctgcag 212
             ||||||||||||||||||||
Sbjct: 68391 attgaaggtgactgctgcag 68372


>gi|23496259|gb|AE014841.1| Plasmodium falciparum 3D7 chromosome 11 section 6 of 8 of the complete
              sequence
          Length = 252420

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 23/24 (95%)
 Strand = Plus / Plus

                                      
Query: 349    gatgatggtaacaaatatatcacc 372
              ||||||| ||||||||||||||||
Sbjct: 154958 gatgatgataacaaatatatcacc 154981


>gi|21490079|gb|AC108734.10| Homo sapiens 3 BAC RP11-259P15 (Roswell Park Cancer Institute Human BAC
             Library) complete sequence
          Length = 125990

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Minus

                                 
Query: 902   aagctcaaattactgataag 921
             ||||||||||||||||||||
Sbjct: 45671 aagctcaaattactgataag 45652


>gi|22549867|gb|AC100821.2| Homo sapiens chromosome 8, clone RP11-30L15, complete sequence
          Length = 183976

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 23/24 (95%)
 Strand = Plus / Minus

                                     
Query: 1036  aaattctttttctatggaattctg 1059
             ||||||||||||||||| ||||||
Sbjct: 62883 aaattctttttctatggtattctg 62860


>gi|22382034|gb|AC060764.13| Homo sapiens chromosome 8, clone RP11-626A5, complete sequence
          Length = 184338

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 23/24 (95%)
 Strand = Plus / Minus

                                      
Query: 1036   aaattctttttctatggaattctg 1059
              ||||||||||||||||| ||||||
Sbjct: 176396 aaattctttttctatggtattctg 176373


>gi|14336745|gb|AE006467.1| Homo sapiens 16p13.3 sequence section 6 of 8
          Length = 279011

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Plus

                                  
Query: 790    tgctcttgtgaagatgaaag 809
              ||||||||||||||||||||
Sbjct: 227753 tgctcttgtgaagatgaaag 227772


>gi|21539149|gb|AC010063.7| Drosophila melanogaster 3L BAC RP98-16A3 (Roswell Park Cancer Institute
              Drosophila BAC Library) complete sequence
          Length = 194006

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Minus

                                  
Query: 1042   tttttctatggaattctgaa 1061
              ||||||||||||||||||||
Sbjct: 119502 tttttctatggaattctgaa 119483


>gi|19424444|gb|AC093180.12| Oryza sativa chromosome 3 BAC OJ1004_D04 genomic sequence, complete
              sequence
          Length = 158170

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Minus

                                  
Query: 441    caagtcatcttcttcaagtg 460
              ||||||||||||||||||||
Sbjct: 149732 caagtcatcttcttcaagtg 149713


>gi|16445200|gb|AC096736.3| Homo sapiens BAC clone RP11-171N4 from 4, complete sequence
          Length = 172989

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Plus

                                 
Query: 1030  tttgaaaaattctttttcta 1049
             ||||||||||||||||||||
Sbjct: 88791 tttgaaaaattctttttcta 88810


>gi|15292546|gb|AY052118.1| Drosophila melanogaster SD06673 full length cDNA
          Length = 2235

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Plus

                                
Query: 1042 tttttctatggaattctgaa 1061
            ||||||||||||||||||||
Sbjct: 2176 tttttctatggaattctgaa 2195


>gi|1122811|emb|Z68217.1|CEF58G6 Caenorhabditis elegans cosmid F58G6, complete sequence
          Length = 31586

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 23/24 (95%)
 Strand = Plus / Plus

                                    
Query: 854  tgaattcttatattcaacaaagtg 877
            |||||||| |||||||||||||||
Sbjct: 4915 tgaattctaatattcaacaaagtg 4938


>gi|23894970|emb|AL772352.7| Mouse DNA sequence from clone RP23-147F6 on chromosome 2, complete
             sequence
          Length = 204418

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Minus

                                 
Query: 148   gtagactctacatcgcaaag 167
             ||||||||||||||||||||
Sbjct: 21391 gtagactctacatcgcaaag 21372


>gi|24474462|emb|AL713972.11| Mouse DNA sequence from clone RP23-305L4 on chromosome X, complete
              sequence
          Length = 201476

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Minus

                                  
Query: 629    atattttacaagaaaactac 648
              ||||||||||||||||||||
Sbjct: 159092 atattttacaagaaaactac 159073


>gi|11323377|gb|AC069247.5|AC069247 Homo sapiens chromosome 3 clone RP11-489O22 map 3p, complete sequence
          Length = 180234

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Minus

                                  
Query: 193    attgaaggtgactgctgcag 212
              ||||||||||||||||||||
Sbjct: 128722 attgaaggtgactgctgcag 128703


>gi|13937407|emb|AL031719.12|HS380F5 Human DNA sequence from clone LA16-380F5 on chromosome 16. Contains
             part of the gene KIAA0590, ESTs, STSs, GSSs and three
             putative CpG islands, complete sequence
          Length = 44653

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Plus

                                 
Query: 790   tgctcttgtgaagatgaaag 809
             ||||||||||||||||||||
Sbjct: 39937 tgctcttgtgaagatgaaag 39956


>gi|16304960|emb|AL590086.4| Human DNA sequence from clone RP11-62J23 on chromosome 13, complete
             sequence
          Length = 24524

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Plus

                                 
Query: 630   tattttacaagaaaactaca 649
             ||||||||||||||||||||
Sbjct: 11290 tattttacaagaaaactaca 11309


>gi|3818397|gb|AC002308.1|AC002308 Homo sapiens Chromosome 22q11.2 BAC Clone 1000e4 In IGLC Region, complete
              sequence
          Length = 151111

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Minus

                                  
Query: 519    taagaaagataaatcacaga 538
              ||||||||||||||||||||
Sbjct: 136550 taagaaagataaatcacaga 136531



 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Minus

                                 
Query: 519   taagaaagataaatcacaga 538
             ||||||||||||||||||||
Sbjct: 70975 taagaaagataaatcacaga 70956


>gi|11414464|emb|AL138919.12| Human DNA sequence from clone RP3-492L20 on chromosome 6 Contains STSs
             and GSSs, complete sequence
          Length = 72535

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Minus

                                 
Query: 932   atttggatgattgtaaatgc 951
             ||||||||||||||||||||
Sbjct: 64527 atttggatgattgtaaatgc 64508


>gi|18077706|emb|AL606517.14| Human DNA sequence from clone RP11-182I10 on chromosome 1, complete
             sequence
          Length = 74530

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Minus

                                 
Query: 936   ggatgattgtaaatgcactg 955
             ||||||||||||||||||||
Sbjct: 22032 ggatgattgtaaatgcactg 22013


>gi|6478942|gb|AC012331.9|AC012331 Homo sapiens, complete sequence
          Length = 143376

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Plus

                                 
Query: 519   taagaaagataaatcacaga 538
             ||||||||||||||||||||
Sbjct: 46618 taagaaagataaatcacaga 46637


>gi|26082020|dbj|AK030853.1| Mus musculus adult male thymus cDNA, RIKEN full-length enriched
            library, clone:5830428M17 product:unclassifiable, full
            insert sequence
          Length = 3819

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Minus

                                
Query: 679  tcagaaacactcaccccaca 698
            ||||||||||||||||||||
Sbjct: 2674 tcagaaacactcaccccaca 2655


>gi|3560254|emb|AL031535.1|SPCC16C4 S.pombe chromosome III cosmid c16C4
          Length = 44751

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Minus

                                 
Query: 1077  gaaaactcaaataaaattca 1096
             ||||||||||||||||||||
Sbjct: 27491 gaaaactcaaataaaattca 27472


>gi|18307724|dbj|AP001324.4| Homo sapiens genomic DNA, chromosome 11q clone:RP11-864N7, complete
              sequences
          Length = 230157

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Plus

                                  
Query: 682    gaaacactcaccccacaaag 701
              ||||||||||||||||||||
Sbjct: 111128 gaaacactcaccccacaaag 111147


>gi|2114216|dbj|D86994.1| Homo sapiens immunoglobulin lambda gene locus DNA, clone:102D1
          Length = 37760

 Score = 40.1 bits (20), Expect = 8.0
 Identities = 20/20 (100%)
 Strand = Plus / Minus

                                
Query: 519  taagaaagataaatcacaga 538
            ||||||||||||||||||||
Sbjct: 8966 taagaaagataaatcacaga 8947


  Database: All GenBank+EMBL+DDBJ+PDB sequences (but no EST, STS, GSS,
  or phase 0, 1 or 2 HTGS sequences)
    Posted date:  Mar 19, 2003 10:12 PM
  Number of letters in database: -669,803,131
  Number of sequences in database:  1,706,607
  
Lambda     K      H
    1.37    0.711     1.31 

Gapped
Lambda     K      H
    1.37    0.711     1.31 


Matrix: blastn matrix:1 -3
Gap Penalties: Existence: 5, Extension: 2
Number of Hits to DB: 6,017,395
Number of Sequences: 1706607
Number of extensions: 6017395
Number of successful extensions: 31316
Number of sequences better than 10.0: 52
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 31233
Number of HSP's gapped (non-prelim): 80
length of query: 1254
length of database: 7,920,131,457
effective HSP length: 22
effective length of query: 1232
effective length of database: 7,882,586,103
effective search space: 9711346078896
effective search space used: 9711346078896
T: 0
A: 0
X1: 6 (11.9 bits)
X2: 15 (29.7 bits)
S1: 12 (24.3 bits)
S2: 20 (40.1 bits)





 
BLASTX 2.2.5 [Nov-16-2002]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.
RID: 1048225152-06655-23510
Query= 
         (1254 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF 
           1,375,764 sequences; 441,946,756 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|6323663|ref|NP_013734.1| metal-binding transcriptional activa...   836   0.0  
gi|406767|emb|CAA52645.1| MAC1 protein [Saccharomyces cerevisiae]     833   0.0  
gi|19075723|ref|NP_588223.1| putative metal-binding regulatory p...    61   4e-08
gi|6325265|ref|NP_015333.1| Homolog of Ace1 Activator; Haa1p [Sa...    57   8e-07
gi|763007|emb|CAA88786.1| unknown [Saccharomyces cerevisiae]           57   8e-07
gi|19113835|ref|NP_592923.1| Cu metalloregulatory transcription ...    55   2e-06
gi|1169093|sp|P45815|CRF1_YARLI Copper resistance protein CRF1 >...    54   4e-06
gi|6321272|ref|NP_011349.1| Upregulates metallothionein (CUP1) e...    53   9e-06
gi|171340|gb|AAA34542.1| Cu-dependent DNA-binding protein              53   9e-06
gi|28921705|gb|EAA30986.1| hypothetical protein [Neurospora crassa]    51   3e-05
gi|1168451|sp|P41772|AMT1_CANGA Metal-activated transcriptional ...    50   7e-05
gi|7493978|pir||S72468 probable transcription factor grisea - Po...    49   2e-04
gi|28921879|gb|EAA31153.1| predicted protein [Neurospora crassa]       49   2e-04
gi|5542205|pdb|1CO4|A Chain A, Solution Structure Of A Zinc Doma...    47   5e-04
gi|971389|emb|CAA59765.1| ACE1 [Saccharomyces cerevisiae]              43   0.009
gi|15639844|ref|NP_219294.1| T. pallidum predicted coding region...    37   0.65 
gi|14285958|sp|O83830|Y858_TREPA Hypothetical protein TP0858 pre...    37   0.65 
gi|6324683|ref|NP_014752.1| Synaptojanin-like protein; Inp53p [S...    35   1.9  
gi|17367423|sp|Q9WTQ2|PODX_RAT Podocalyxin precursor >gi|4996222...    35   2.5  
gi|20301990|ref|NP_620203.1| podocalyxin-like [Rattus norvegicus...    35   2.5  
gi|21322664|emb|CAC87883.2| alpha2 b2 adrenergic receptor [Takif...    35   3.2  
gi|24324059|ref|NP_715423.1| Glutamine phosphoribosylpyrophospha...    34   4.2  
gi|7482005|pir||T18355 hypothetical protein P3 - Mycoplasma hyor...    34   4.2  
gi|25024336|ref|XP_204871.1| similar to KIAA1662 protein [Homo s...    34   4.2  
gi|20904033|ref|XP_139468.1| similar to KIAA1662 protein [Homo s...    34   4.2  
gi|24663799|ref|NP_648645.1| CG10713-PA [Drosophila melanogaster...    33   9.3  
gi|19115042|ref|NP_594130.1| putative glucoamylase I (alpha-1,4-...    33   9.3  
gi|27731153|ref|XP_218521.1| similar to ribosomal protein L27 [R...    33   9.3  
gi|15232144|ref|NP_189370.1| hypothetical protein; protein id: A...    33   9.3  

ALIGNMENTS
>gi|6323663|ref|NP_013734.1| metal-binding transcriptional activator; Mac1p [Saccharomyces
            cerevisiae]
 gi|1708907|sp|P35192|MAC1_YEAST Metal binding activator 1
 gi|1078094|pir||S54023 probable transcription factor MAC1 - yeast (Saccharomyces cerevisiae)
 gi|798932|emb|CAA89124.1| Mac1p [Saccharomyces cerevisiae]
          Length = 417

 Score =  836 bits (2159), Expect = 0.0
 Identities = 404/417 (96%), Positives = 404/417 (96%)
 Frame = +1

Query: 1    MIIFNGNKYACASCIRGHRSSTCRHSHRMLIKVRTRGRPSPMAIRDAILVDSTSQSTEYE 180
            MIIFNGNKYACASCIRGHRSSTCRHSHRMLIKVRTRGRPSPMAIRDAILVDSTSQSTEYE
Sbjct: 1    MIIFNGNKYACASCIRGHRSSTCRHSHRMLIKVRTRGRPSPMAIRDAILVDSTSQSTEYE 60

Query: 181  NGAQIEGDCCSAMNQQPILFVRASAVRKARMINGKLHILMEEGFTAHEPKDISTFTDDGN 360
            NGAQIEGDCCSAMNQQPILFVRASAVRKARMINGKLHILMEEGFTAHEPKDISTFTDDGN
Sbjct: 61   NGAQIEGDCCSAMNQQPILFVRASAVRKARMINGKLHILMEEGFTAHEPKDISTFTDDGN 120

Query: 361  KYITETEFLRKHSPKAPATGTISPDSTXXXXXXXXXXXXXLQQEPIRHFSNCCKKDKSQN 540
            KYITETEFLRKHSPKAPATGTISPDST             LQQEPIRHFSNCCKKDKSQN
Sbjct: 121  KYITETEFLRKHSPKAPATGTISPDSTKSSSSSEKKERSRLQQEPIRHFSNCCKKDKSQN 180

Query: 541  PASNGKTNKAPSDDIFTPYGSLESTSAFNDILQENYNSSVPGAHDSSETLTPQSTTTIAA 720
            PASNGKTNKAPSDDIFTPYGSLESTSAFNDILQENYNSSVPGAHDSSETLTPQSTTTIAA
Sbjct: 181  PASNGKTNKAPSDDIFTPYGSLESTSAFNDILQENYNSSVPGAHDSSETLTPQSTTTIAA 240

Query: 721  PHSSDVASKVEVLTHKGIFLSTQCSCEDESCPCVNCLIHRSEEELNSYIQQSGVPLTNIG 900
            PHSSDVASKVEVLTHKGIFLSTQCSCEDESCPCVNCLIHRSEEELNSYIQQSGVPLTNIG
Sbjct: 241  PHSSDVASKVEVLTHKGIFLSTQCSCEDESCPCVNCLIHRSEEELNSYIQQSGVPLTNIG 300

Query: 901  EAQITDKMMDYLDDCKCTDKECICPPDNCTCDGCFSHSTNIIPFEKFFFYGILNARLTRK 1080
            EAQITDKMMDYLDDCKCTDKECICPPDNCTCDGCFSHSTNIIPFEKFFFYGILNARLTRK
Sbjct: 301  EAQITDKMMDYLDDCKCTDKECICPPDNCTCDGCFSHSTNIIPFEKFFFYGILNARLTRK 360

Query: 1081 TQIKFKGKLVPSKYWWDFLKLQVPLMTDAQLELLDIHAWFQKLVSNYAPHLSDATTS 1251
            TQIKFKGKLVPSKYWWDFLKLQVPLMTDAQLELLDIHAWFQKLVSNYAPHLSDATTS
Sbjct: 361  TQIKFKGKLVPSKYWWDFLKLQVPLMTDAQLELLDIHAWFQKLVSNYAPHLSDATTS 417


>gi|406767|emb|CAA52645.1| MAC1 protein [Saccharomyces cerevisiae]
          Length = 417

 Score =  833 bits (2151), Expect = 0.0
 Identities = 403/417 (96%), Positives = 403/417 (96%)
 Frame = +1

Query: 1    MIIFNGNKYACASCIRGHRSSTCRHSHRMLIKVRTRGRPSPMAIRDAILVDSTSQSTEYE 180
            MIIFNGNKYACASCIRGHRSSTCRHSHRMLIKVRTRGRPSPMAIRDAILVDSTSQSTEYE
Sbjct: 1    MIIFNGNKYACASCIRGHRSSTCRHSHRMLIKVRTRGRPSPMAIRDAILVDSTSQSTEYE 60

Query: 181  NGAQIEGDCCSAMNQQPILFVRASAVRKARMINGKLHILMEEGFTAHEPKDISTFTDDGN 360
            NGAQIEGDCCSAMNQQPILFVRASAVRKARMINGKLHILMEEGFTAHEPKDISTFTDDGN
Sbjct: 61   NGAQIEGDCCSAMNQQPILFVRASAVRKARMINGKLHILMEEGFTAHEPKDISTFTDDGN 120

Query: 361  KYITETEFLRKHSPKAPATGTISPDSTXXXXXXXXXXXXXLQQEPIRHFSNCCKKDKSQN 540
            KYITETEFLRKHSPKAPATGTISPDST             LQQEPIRHFSNCCKKDKSQN
Sbjct: 121  KYITETEFLRKHSPKAPATGTISPDSTKSSSSSEKKERSRLQQEPIRHFSNCCKKDKSQN 180

Query: 541  PASNGKTNKAPSDDIFTPYGSLESTSAFNDILQENYNSSVPGAHDSSETLTPQSTTTIAA 720
            PASNGKTNKAPSDDIFT YGSLESTSAFNDILQENYNSSVPGAHDSSETLTPQSTTTIAA
Sbjct: 181  PASNGKTNKAPSDDIFTAYGSLESTSAFNDILQENYNSSVPGAHDSSETLTPQSTTTIAA 240

Query: 721  PHSSDVASKVEVLTHKGIFLSTQCSCEDESCPCVNCLIHRSEEELNSYIQQSGVPLTNIG 900
            PHSSDVASKVEVLTHKGIFLSTQCSCEDESCPCVNCLIHRSEEELNSYIQQSGVPLTNIG
Sbjct: 241  PHSSDVASKVEVLTHKGIFLSTQCSCEDESCPCVNCLIHRSEEELNSYIQQSGVPLTNIG 300

Query: 901  EAQITDKMMDYLDDCKCTDKECICPPDNCTCDGCFSHSTNIIPFEKFFFYGILNARLTRK 1080
            EAQITDKMMDYLDDCKCTDKECICPPDNCTCDGCFSHSTNIIPFEKFFFYGILNARLTRK
Sbjct: 301  EAQITDKMMDYLDDCKCTDKECICPPDNCTCDGCFSHSTNIIPFEKFFFYGILNARLTRK 360

Query: 1081 TQIKFKGKLVPSKYWWDFLKLQVPLMTDAQLELLDIHAWFQKLVSNYAPHLSDATTS 1251
            TQIKFKGKLVPSKYWWDFLKLQVPLMTDAQLELLDIHAWFQKLVSNYAPHLSDATTS
Sbjct: 361  TQIKFKGKLVPSKYWWDFLKLQVPLMTDAQLELLDIHAWFQKLVSNYAPHLSDATTS 417


>gi|19075723|ref|NP_588223.1| putative metal-binding regulatory protein [Schizosaccharomyces
           pombe]
 gi|15213958|sp|O94588|CUF2_SCHPO Copper-binding regulatory protein cuf2 (Copper homeostasis protein)
 gi|11290733|pir||T43665 probable copper homeostasis protein - fission yeast
           (Schizosaccharomyces pombe)
 gi|3819702|emb|CAA21819.1| putative metal-binding regulatory protein [Schizosaccharomyces
           pombe]
 gi|5706544|emb|CAB52306.1| copper homeostasis protein [Schizosaccharomyces pombe]
          Length = 177

 Score = 60.8 bits (146), Expect = 4e-08
 Identities = 25/39 (64%), Positives = 30/39 (76%)
 Frame = +1

Query: 1   MIIFNGNKYACASCIRGHRSSTCRHSHRMLIKVRTRGRP 117
           MII +G  YAC  C+RGHR S+C+H  R LI+VRTRGRP
Sbjct: 1   MIIIDGKNYACVVCLRGHRGSSCQHQERALIEVRTRGRP 39


>gi|6325265|ref|NP_015333.1| Homolog of Ace1 Activator; Haa1p [Saccharomyces cerevisiae]
 gi|17366444|sp|Q12753|HAA1_YEAST Transcriptional activator HAA1
 gi|2132257|pir||S59753 hypothetical protein YPR008w - yeast (Saccharomyces cerevisiae)
 gi|939742|gb|AAA97587.1| Lpz8p
 gi|1314083|emb|CAA95048.1| unknown [Saccharomyces cerevisiae]
          Length = 694

 Score = 56.6 bits (135), Expect = 8e-07
 Identities = 40/140 (28%), Positives = 61/140 (43%)
 Frame = +1

Query: 1   MIIFNGNKYACASCIRGHRSSTCRHSHRMLIKVRTRGRPSPMAIRDAILVDSTSQSTEYE 180
           M++ NG KYAC  CIRGHR +TC H+ + L+ ++ +GRPS          D   Q  + +
Sbjct: 1   MVLINGIKYACERCIRGHRVTTCNHTDQPLMMIKPKGRPSTTC-------DYCKQLRKNK 53

Query: 181 NGAQIEGDCCSAMNQQPILFVRASAVRKARMINGKLHILMEEGFTAHEPKDISTFTDDGN 360
           N A  EG C     ++  L  +A    +A+                 + K  +  TD+  
Sbjct: 54  N-ANPEGVCTCGRLEKKKLAQKAKEEARAKA-------------KEKQRKQCTCGTDEVC 99

Query: 361 KYITETEFLRKHSPKAPATG 420
           KY  +   LRK    +   G
Sbjct: 100 KYHAQKRHLRKSPSSSQKKG 119


>gi|763007|emb|CAA88786.1| unknown [Saccharomyces cerevisiae]
          Length = 153

 Score = 56.6 bits (135), Expect = 8e-07
 Identities = 40/140 (28%), Positives = 61/140 (43%)
 Frame = +1

Query: 1   MIIFNGNKYACASCIRGHRSSTCRHSHRMLIKVRTRGRPSPMAIRDAILVDSTSQSTEYE 180
           M++ NG KYAC  CIRGHR +TC H+ + L+ ++ +GRPS          D   Q  + +
Sbjct: 1   MVLINGIKYACERCIRGHRVTTCNHTDQPLMMIKPKGRPSTTC-------DYCKQLRKNK 53

Query: 181 NGAQIEGDCCSAMNQQPILFVRASAVRKARMINGKLHILMEEGFTAHEPKDISTFTDDGN 360
           N A  EG C     ++  L  +A    +A+                 + K  +  TD+  
Sbjct: 54  N-ANPEGVCTCGRLEKKKLAQKAKEEARAKA-------------KEKQRKQCTCGTDEVC 99

Query: 361 KYITETEFLRKHSPKAPATG 420
           KY  +   LRK    +   G
Sbjct: 100 KYHAQKRHLRKSPSSSQKKG 119


>gi|19113835|ref|NP_592923.1| Cu metalloregulatory transcription factor 1 [Schizosaccharomyces
           pombe]
 gi|1175405|sp|Q09728|CUF1_SCHPO Metal-binding regulatory protein cuf1
 gi|2130422|pir||S58105 Cu metalloregulatory transcription factor 1 Cuf1 - fission yeast
           (Schizosaccharomyces pombe)
 gi|914889|emb|CAA90469.1| Cu metalloregulatory transcription factor 1 [Schizosaccharomyces
           pombe]
 gi|5706540|emb|CAB52304.1| copper-sensing transcription factor [Schizosaccharomyces pombe]
 gi|5759269|gb|AAD51063.1| Cuf1 protein [Schizosaccharomyces pombe]
          Length = 411

 Score = 55.5 bits (132), Expect = 2e-06
 Identities = 22/39 (56%), Positives = 28/39 (71%)
 Frame = +1

Query: 1   MIIFNGNKYACASCIRGHRSSTCRHSHRMLIKVRTRGRP 117
           M++ N  K AC  CIRGHRSSTC+H+ R L  +R +GRP
Sbjct: 1   MVVINNVKMACMKCIRGHRSSTCKHNDRELFPIRPKGRP 39


>gi|1169093|sp|P45815|CRF1_YARLI Copper resistance protein CRF1
 gi|473176|emb|CAA80803.1| Product required for copper resistance [Yarrowia lipolytica]
          Length = 411

 Score = 54.3 bits (129), Expect = 4e-06
 Identities = 20/44 (45%), Positives = 31/44 (70%)
 Frame = +1

Query: 1   MIIFNGNKYACASCIRGHRSSTCRHSHRMLIKVRTRGRPSPMAI 132
           M++  G KYAC  CIRGHR S+C H+ + LI+++ +GRP+   +
Sbjct: 1   MVVIEGIKYACERCIRGHRVSSCTHTQQPLIRIKPKGRPATQCL 44


>gi|6321272|ref|NP_011349.1| Upregulates metallothionein (CUP1) expression in response to Cu2+;
           Cup2p [Saccharomyces cerevisiae]
 gi|113021|sp|P15315|ACE1_YEAST Transcriptional activator protein ACE1 (Copper-fist transcription
           factor)
 gi|83564|pir||A31926 transcription activator ACE1 - yeast (Saccharomyces cerevisiae)
 gi|170974|gb|AAA34386.1| ACE1
 gi|170978|gb|AAA66313.1| transcriptional activator protein
 gi|728691|emb|CAA88533.1| ACE1/CUP2 [Saccharomyces cerevisiae]
 gi|1322764|emb|CAA96877.1| ORF YGL166w [Saccharomyces cerevisiae]
          Length = 225

 Score = 53.1 bits (126), Expect = 9e-06
 Identities = 21/40 (52%), Positives = 29/40 (72%)
 Frame = +1

Query: 1   MIIFNGNKYACASCIRGHRSSTCRHSHRMLIKVRTRGRPS 120
           M++ NG KYAC +CIRGHR++ C H+   L  +R +GRPS
Sbjct: 1   MVVINGVKYACETCIRGHRAAQCTHTDGPLQMIRRKGRPS 40


>gi|171340|gb|AAA34542.1| Cu-dependent DNA-binding protein
          Length = 48

 Score = 53.1 bits (126), Expect = 9e-06
 Identities = 21/40 (52%), Positives = 29/40 (72%)
 Frame = +1

Query: 1   MIIFNGNKYACASCIRGHRSSTCRHSHRMLIKVRTRGRPS 120
           M++ NG KYAC +CIRGHR++ C H+   L  +R +GRPS
Sbjct: 1   MVVINGVKYACETCIRGHRAAQCTHTDGPLQMIRRKGRPS 40


>gi|28921705|gb|EAA30986.1| hypothetical protein [Neurospora crassa]
          Length = 565

 Score = 51.2 bits (121), Expect = 3e-05
 Identities = 24/40 (60%), Positives = 28/40 (70%), Gaps = 1/40 (2%)
 Frame = +1

Query: 1   MIIFNGNKYACASCIRGHRSSTCRH-SHRMLIKVRTRGRP 117
           M I NG K ACA CIRGHRS+ C H S R+++ VR  GRP
Sbjct: 1   MPIINGQKMACAPCIRGHRSTKCTHASERVMVPVRKPGRP 40


>gi|1168451|sp|P41772|AMT1_CANGA Metal-activated transcriptional activator protein AMT1
 gi|101986|pir||A41116 transcription factor AMT1, metal-inducible - yeast (Candida
           glabrata)
 gi|173320|gb|AAA35271.1| metal-activated transcription factor
          Length = 265

 Score = 50.1 bits (118), Expect = 7e-05
 Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 12/99 (12%)
 Frame = +1

Query: 1   MIIFNGNKYACASCIRGHRSSTCRHSHRMLIKVRTRGRPSPMA-----IRDAILVD---- 153
           M++ NG KYAC SCI+ H+++ C H+ R L  ++ RGRP         +R    V+    
Sbjct: 1   MVVINGVKYACDSCIKSHKAAQCEHNDRPLKILKPRGRPPTTCDHCKDMRKTKNVNPSGS 60

Query: 154 ---STSQSTEYENGAQIEGDCCSAMNQQPILFVRASAVR 261
              S  +    E G  IE D   + N    L VR    R
Sbjct: 61  CNCSKLEKIRQEKGITIEEDMLMSGNMDMCLCVRGEPCR 99


>gi|7493978|pir||S72468 probable transcription factor grisea - Podospora anserina
 gi|1531573|emb|CAA61598.1| GRISEA protein [Podospora anserina]
          Length = 597

 Score = 48.9 bits (115), Expect = 2e-04
 Identities = 22/40 (55%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
 Frame = +1

Query: 1   MIIFNGNKYACASCIRGHRSSTCRH-SHRMLIKVRTRGRP 117
           M I NG K AC  CIRGHRS+ C H + R+++ VR  GRP
Sbjct: 1   MPIINGQKMACGPCIRGHRSTKCNHYNERVMVPVRKPGRP 40



 Score = 33.5 bits (75), Expect = 7.2
 Identities = 15/46 (32%), Positives = 23/46 (50%)
 Frame = +1

Query: 781 STQCSCEDESCPCVNCLIHRSEEELNSYIQQSGVPLTNIGEAQITD 918
           S +C C  E C CV CL H    ++  Y+Q +  P ++ G +   D
Sbjct: 435 SHECGC-GEGCQCVGCLAHPFNSQMLQYVQNAYSPNSSHGNSGSAD 479


>gi|28921879|gb|EAA31153.1| predicted protein [Neurospora crassa]
          Length = 434

 Score = 48.5 bits (114), Expect = 2e-04
 Identities = 18/38 (47%), Positives = 26/38 (68%)
 Frame = +1

Query: 4   IIFNGNKYACASCIRGHRSSTCRHSHRMLIKVRTRGRP 117
           ++ NG K+AC +C+RGHR S C+H  R L  +  +GRP
Sbjct: 1   MLINGEKWACEACVRGHRVSNCQHHDRPLQHINKKGRP 38


>gi|5542205|pdb|1CO4|A Chain A, Solution Structure Of A Zinc Domain Conserved In Yeast
           Copper-Regulated Transcription Factors
          Length = 42

 Score = 47.4 bits (111), Expect = 5e-04
 Identities = 18/38 (47%), Positives = 27/38 (71%)
 Frame = +1

Query: 4   IIFNGNKYACASCIRGHRSSTCRHSHRMLIKVRTRGRP 117
           ++ NG KYAC SCI+ H+++ C H+ R L  ++ RGRP
Sbjct: 2   VVINGVKYACDSCIKSHKAAQCEHNDRPLKILKPRGRP 39


>gi|971389|emb|CAA59765.1| ACE1 [Saccharomyces cerevisiae]
          Length = 33

 Score = 43.1 bits (100), Expect = 0.009
 Identities = 15/26 (57%), Positives = 21/26 (80%)
 Frame = +1

Query: 1  MIIFNGNKYACASCIRGHRSSTCRHS 78
          M++ NG KYAC +CIRGHR++ C H+
Sbjct: 1  MVVINGVKYACETCIRGHRAAQCTHT 26


>gi|15639844|ref|NP_219294.1| T. pallidum predicted coding region TP0858 [Treponema pallidum]
 gi|7519602|pir||B71272 hypothetical protein TP0858 - syphilis spirochete
 gi|3323177|gb|AAC65829.1| T. pallidum predicted coding region TP0858 [Treponema pallidum]
          Length = 408

 Score = 37.0 bits (84), Expect = 0.65
 Identities = 19/53 (35%), Positives = 31/53 (58%)
 Frame = +1

Query: 841 SEEELNSYIQQSGVPLTNIGEAQITDKMMDYLDDCKCTDKECICPPDNCTCDG 999
           + EE N YI   G+  TN+G   +T K+ D +++C  T ++C C  + C C+G
Sbjct: 213 TSEEPNLYI---GLAATNLG---LTVKVSDKIENCTSTCEKCGCCKERCCCNG 259


>gi|14285958|sp|O83830|Y858_TREPA Hypothetical protein TP0858 precursor
          Length = 396

 Score = 37.0 bits (84), Expect = 0.65
 Identities = 19/53 (35%), Positives = 31/53 (58%)
 Frame = +1

Query: 841 SEEELNSYIQQSGVPLTNIGEAQITDKMMDYLDDCKCTDKECICPPDNCTCDG 999
           + EE N YI   G+  TN+G   +T K+ D +++C  T ++C C  + C C+G
Sbjct: 201 TSEEPNLYI---GLAATNLG---LTVKVSDKIENCTSTCEKCGCCKERCCCNG 247


>gi|6324683|ref|NP_014752.1| Synaptojanin-like protein; Inp53p [Saccharomyces cerevisiae]
 gi|2132889|pir||S61667 probable membrane protein YOR109w - yeast (Saccharomyces cerevisiae)
 gi|1164954|emb|CAA64029.1| YOR3231w [Saccharomyces cerevisiae]
 gi|1420295|emb|CAA99307.1| ORF YOR109w [Saccharomyces cerevisiae]
          Length = 1107

 Score = 35.4 bits (80), Expect = 1.9
 Identities = 25/70 (35%), Positives = 34/70 (48%), Gaps = 4/70 (5%)
 Frame = +1

Query: 541  PASNGKTNKAPSDDIFTPYGSLESTSAFNDILQEN----YNSSVPGAHDSSETLTPQSTT 708
            PA +    K+P     TP  S  S S+    +QEN     N  +P    S   LTP+ST+
Sbjct: 977  PAPSTSKEKSP-----TPQTSTASLSSVTKNIQENKPLAQNRRIPPPGFSQNILTPKSTS 1031

Query: 709  TIAAPHSSDV 738
             +A+P SS V
Sbjct: 1032 NLASPMSSKV 1041


>gi|17367423|sp|Q9WTQ2|PODX_RAT Podocalyxin precursor
 gi|4996222|dbj|BAA78375.1| podocalyxin [Rattus norvegicus]
          Length = 485

 Score = 35.0 bits (79), Expect = 2.5
 Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 1/70 (1%)
 Frame = +1

Query: 526 DKSQN-PASNGKTNKAPSDDIFTPYGSLESTSAFNDILQENYNSSVPGAHDSSETLTPQS 702
           D++Q+ PA+N  +N  P   +  P  +  STS+ +    ++ NSSV    DS+   T  S
Sbjct: 40  DQNQDKPATNQPSNATPKSSVQPPTPTSISTSSPDPKATQSSNSSVTTTSDSTTDRTSSS 99

Query: 703 TTTIAAPHSS 732
           T+T+    +S
Sbjct: 100 TSTVPTTSNS 109


>gi|20301990|ref|NP_620203.1| podocalyxin-like [Rattus norvegicus]
 gi|6492252|gb|AAF14238.1|AF109393_1 podocalyxin [Rattus norvegicus]
          Length = 485

 Score = 35.0 bits (79), Expect = 2.5
 Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 1/70 (1%)
 Frame = +1

Query: 526 DKSQN-PASNGKTNKAPSDDIFTPYGSLESTSAFNDILQENYNSSVPGAHDSSETLTPQS 702
           D++Q+ PA+N  +N  P   +  P  +  STS+ +    ++ NSSV    DS+   T  S
Sbjct: 40  DQNQDKPATNQPSNATPKSSVQPPTPTSISTSSPDPKATQSSNSSVTTTSDSTTDRTSSS 99

Query: 703 TTTIAAPHSS 732
           T+T+    +S
Sbjct: 100 TSTVPTTSNS 109


>gi|21322664|emb|CAC87883.2| alpha2 b2 adrenergic receptor [Takifugu rubripes]
          Length = 465

 Score = 34.7 bits (78), Expect = 3.2
 Identities = 23/89 (25%), Positives = 40/89 (44%), Gaps = 3/89 (3%)
 Frame = +1

Query: 490 EPIRHFSNCCKKDKSQNPASNGKTNKAPSDDIFTPYGSLESTSAFNDILQENY---NSSV 660
           +P RH     K + S  P+S+  +N  P     TP  +   T   N+    N    +SS 
Sbjct: 203 QPARHVQANGKDEDSTPPSSSKTSNARPPTLAITPSPTPGETQTSNNPSSNNLLHPSSSS 262

Query: 661 PGAHDSSETLTPQSTTTIAAPHSSDVASK 747
           P A  ++ +L   + T++ AP++ +   K
Sbjct: 263 PAATPNAASLESSTPTSVPAPNAKEEGKK 291


>gi|24324059|ref|NP_715423.1| Glutamine phosphoribosylpyrophosphate amidotransferase
            [Wigglesworthia brevipalpis]
 gi|25166269|dbj|BAC24459.1| purF [Wigglesworthia brevipalpis]
          Length = 470

 Score = 34.3 bits (77), Expect = 4.2
 Identities = 41/157 (26%), Positives = 67/157 (42%), Gaps = 9/157 (5%)
 Frame = +1

Query: 724  HSSDVASKVEVL-THKGIFLSTQCSCEDESCPCVNCLIHRSEEELNSYIQQSGVPLTNIG 900
            H  DVA    VL T+ G  L+ QCS     CPC+   I+ S  +  S I +  V    + 
Sbjct: 220  HLRDVAPGEGVLLTNSGKLLTKQCSLTSNYCPCLFEYIYFSRPD--SIIDKISVYTARMK 277

Query: 901  EAQITDKMMDYLDDCKCTDKECICPPDNCTCDGCFSHSTNI-IPFEKFFFYG-------I 1056
              QI  K +    + K  + + + P    +CD     +  + IP+ + F          I
Sbjct: 278  MGQILGKKIS--REWKNLNIDAVIPIPETSCDVALEIARILKIPYRQGFVKNRYVGRTFI 335

Query: 1057 LNARLTRKTQIKFKGKLVPSKYWWDFLKLQVPLMTDA 1167
            ++    RK  I++K  +  +    +F K QV L+ D+
Sbjct: 336  MSNPSIRKKSIRYKFNVNKA----EFYKKQVLLVDDS 368


>gi|7482005|pir||T18355 hypothetical protein P3 - Mycoplasma hyorhinis
 gi|664956|gb|AAA62228.1| P3 ORF
          Length = 1187

 Score = 34.3 bits (77), Expect = 4.2
 Identities = 18/70 (25%), Positives = 27/70 (38%)
 Frame = +1

Query: 784 TQCSCEDESCPCVNCLIHRSEEELNSYIQQSGVPLTNIGEAQITDKMMDYLDDCKCTDKE 963
           T+ SC+ E+C C  C  + S  EL    Q++                    + C C ++ 
Sbjct: 347 TEESCDCEACKCQECEENCSCSELTCGCQEATCSCAQ--------------EHCGCQEES 392

Query: 964 CICPPDNCTC 993
           C CP   C C
Sbjct: 393 CACPNTTCAC 402



 Score = 34.3 bits (77), Expect = 4.2
 Identities = 18/70 (25%), Positives = 27/70 (38%)
 Frame = +1

Query: 784 TQCSCEDESCPCVNCLIHRSEEELNSYIQQSGVPLTNIGEAQITDKMMDYLDDCKCTDKE 963
           T+ SC+ E+C C  C  + S  EL    Q++                    + C C ++ 
Sbjct: 803 TEESCDCEACKCQECEENCSCSELTCGCQEATCSCAQ--------------EHCGCQEES 848

Query: 964 CICPPDNCTC 993
           C CP   C C
Sbjct: 849 CACPNTTCAC 858



 Score = 33.1 bits (74), Expect = 9.3
 Identities = 15/69 (21%), Positives = 26/69 (37%)
 Frame = +1

Query: 790 CSCEDESCPCVNCLIHRSEEELNSYIQQSGVPLTNIGEAQITDKMMDYLDDCKCTDKECI 969
           CSC + +C C       ++E      +    P T     +         + C+CT+  C 
Sbjct: 365 CSCSELTCGCQEATCSCAQEHCGCQEESCACPNTTCACTE---------EHCECTESTCG 415

Query: 970 CPPDNCTCD 996
           C  + C C+
Sbjct: 416 CENEPCECE 424



 Score = 33.1 bits (74), Expect = 9.3
 Identities = 15/69 (21%), Positives = 26/69 (37%)
 Frame = +1

Query: 790  CSCEDESCPCVNCLIHRSEEELNSYIQQSGVPLTNIGEAQITDKMMDYLDDCKCTDKECI 969
            CSC + +C C       ++E      +    P T     +         + C+CT+  C 
Sbjct: 821  CSCSELTCGCQEATCSCAQEHCGCQEESCACPNTTCACTE---------EHCECTESTCG 871

Query: 970  CPPDNCTCD 996
            C  + C C+
Sbjct: 872  CENEPCECE 880



 Score = 33.1 bits (74), Expect = 9.3
 Identities = 16/68 (23%), Positives = 25/68 (36%)
 Frame = +1

Query: 790 CSCEDESCPCVNCLIHRSEEELNSYIQQSGVPLTNIGEAQITDKMMDYLDDCKCTDKECI 969
           C C++ESC C N     +EE         G                   + C+C ++ C 
Sbjct: 842 CGCQEESCACPNTTCACTEEHCECTESTCGCEN----------------EPCECEEEACD 885

Query: 970 CPPDNCTC 993
           C  ++C C
Sbjct: 886 CSEEHCEC 893



 Score = 33.1 bits (74), Expect = 9.3
 Identities = 16/68 (23%), Positives = 25/68 (36%)
 Frame = +1

Query: 790 CSCEDESCPCVNCLIHRSEEELNSYIQQSGVPLTNIGEAQITDKMMDYLDDCKCTDKECI 969
           C C++ESC C N     +EE         G                   + C+C ++ C 
Sbjct: 386 CGCQEESCACPNTTCACTEEHCECTESTCGCEN----------------EPCECEEEACD 429

Query: 970 CPPDNCTC 993
           C  ++C C
Sbjct: 430 CSEEHCEC 437


>gi|25024336|ref|XP_204871.1| similar to KIAA1662 protein [Homo sapiens] [Mus musculus]
          Length = 1725

 Score = 34.3 bits (77), Expect = 4.2
 Identities = 38/145 (26%), Positives = 55/145 (37%), Gaps = 23/145 (15%)
 Frame = +1

Query: 520 KKDKSQNPASNGKTNKAPSDDIFTPYGSLESTSAFNDILQENYNSSVPGAHDSSETLTP- 696
           K+ + Q PA+NG   +AP+    TP  SL+  +A    +Q++   +VP       TL P 
Sbjct: 269 KQIRLQLPAANGSICEAPAPSETTPGPSLK--AAPKRTIQDHPRPAVPLRGVIPGTLPPT 326

Query: 697 --------------QSTTTIAAPH-----SSDVASKVEVLTHKGIFLSTQCSCEDESCPC 819
                         Q   T+  PH     +   AS+     H     + Q S E    PC
Sbjct: 327 VPTKISLGLPFPFGQHRVTVPEPHLHRAPNKTSASRTSSPLHAAPRGAPQTSLESSQPPC 386

Query: 820 VNCLIHRSEEELNS---YIQQSGVP 885
             C+ HR     +S   Y Q    P
Sbjct: 387 TVCIGHRDAPRASSPPRYFQYDPFP 411


>gi|20904033|ref|XP_139468.1| similar to KIAA1662 protein [Homo sapiens] [Mus musculus]
          Length = 1024

 Score = 34.3 bits (77), Expect = 4.2
 Identities = 38/145 (26%), Positives = 55/145 (37%), Gaps = 23/145 (15%)
 Frame = +1

Query: 520 KKDKSQNPASNGKTNKAPSDDIFTPYGSLESTSAFNDILQENYNSSVPGAHDSSETLTP- 696
           K+ + Q PA+NG   +AP+    TP  SL+  +A    +Q++   +VP       TL P 
Sbjct: 219 KQIRLQLPAANGSICEAPAPSETTPGPSLK--AAPKRTIQDHPRPAVPLRGVIPGTLPPT 276

Query: 697 --------------QSTTTIAAPH-----SSDVASKVEVLTHKGIFLSTQCSCEDESCPC 819
                         Q   T+  PH     +   AS+     H     + Q S E    PC
Sbjct: 277 VPTKISLGLPFPFGQHRVTVPEPHLHRAPNKTSASRTSSPLHAAPRGAPQTSLESSQPPC 336

Query: 820 VNCLIHRSEEELNS---YIQQSGVP 885
             C+ HR     +S   Y Q    P
Sbjct: 337 TVCIGHRDAPRASSPPRYFQYDPFP 361


>gi|24663799|ref|NP_648645.1| CG10713-PA [Drosophila melanogaster]
 gi|7294476|gb|AAF49819.1| CG10713-PA [Drosophila melanogaster]
          Length = 475

 Score = 33.1 bits (74), Expect = 9.3
 Identities = 27/98 (27%), Positives = 41/98 (41%), Gaps = 5/98 (5%)
 Frame = +1

Query: 493 PIRHFSNCCKKDKSQNPASNGKTNKAPSDDIFTPYGSLESTSAF---NDILQENYNSSVP 663
           P R  S  C     Q+     ++      D+  P  S +S S++   N +  +    S  
Sbjct: 36  PRRTKSTSCSNSTGQSMPPVHRSLPQTPYDMHQPGTSRQSQSSYGNNNSLHAQQQQHSSS 95

Query: 664 GAHDSSETLTPQSTTTIAAP--HSSDVASKVEVLTHKG 771
           G   ++  LT   TTT A+   H+S +AS   VLT  G
Sbjct: 96  GGTSNNNNLTATGTTTTASNNNHASGIASSAAVLTGSG 133


>gi|19115042|ref|NP_594130.1| putative glucoamylase I (alpha-1,4-glucan glucosidase),
           extracellular starch-degrading enzyme; by similarity to
           S. cerevisiae STA1; contains chitinase family signature
           [Schizosaccharomyces pombe]
 gi|13624759|emb|CAC36921.1| putative glucoamylase I (alpha-1,4-glucan glucosidase),
           extracellular starch-degrading enzyme; by similarity to
           S. cerevisiae STA1; contains chitinase family signature
           [Schizosaccharomyces pombe]
          Length = 1236

 Score = 33.1 bits (74), Expect = 9.3
 Identities = 27/128 (21%), Positives = 52/128 (40%)
 Frame = +1

Query: 499 RHFSNCCKKDKSQNPASNGKTNKAPSDDIFTPYGSLESTSAFNDILQENYNSSVPGAHDS 678
           +H S+    D SQ   S       P+  I +   S  ++SA + I Q+ +  +V    D 
Sbjct: 327 KHSSSKSSHDSSQGLESTSSIALNPTSSISSTSSSSSTSSAISTISQD-HTKTVTSVSDE 385

Query: 679 SETLTPQSTTTIAAPHSSDVASKVEVLTHKGIFLSTQCSCEDESCPCVNCLIHRSEEELN 858
             T+T    T++     +D     + +T   +  ST  S  D +   V+  +    +  +
Sbjct: 386 PTTITASGATSVTTTTKTD----FDTVTTTIVSTSTLISASDSTSIIVSSYVSTVTQPAS 441

Query: 859 SYIQQSGV 882
           + +Q + V
Sbjct: 442 TRVQTTTV 449


>gi|27731153|ref|XP_218521.1| similar to ribosomal protein L27 [Rattus norvegicus]
          Length = 281

 Score = 33.1 bits (74), Expect = 9.3
 Identities = 15/39 (38%), Positives = 23/39 (58%)
 Frame = +1

Query: 1042 FFYGILNARLTRKTQIKFKGKLVPSKYWWDFLKLQVPLM 1158
            F  G L  +  R+T++KF+ +   SK  W F KLQ P++
Sbjct: 113  FKAGALKCKARRETKVKFEERYKMSKNKWSFQKLQAPVI 151



 Score = 33.1 bits (74), Expect = 9.3
 Identities = 15/39 (38%), Positives = 23/39 (58%)
 Frame = +1

Query: 1042 FFYGILNARLTRKTQIKFKGKLVPSKYWWDFLKLQVPLM 1158
            F  G L  +  R+T++KF+ +   SK  W F KLQ P++
Sbjct: 34   FKAGALKCKARRETKVKFEERYKMSKNKWSFQKLQAPVI 72


>gi|15232144|ref|NP_189370.1| hypothetical protein; protein id: At3g27340.1 [Arabidopsis
           thaliana]
          Length = 141

 Score = 33.1 bits (74), Expect = 9.3
 Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 2/50 (4%)
 Frame = +1

Query: 265 ARMINGKLHILMEE--GFTAHEPKDISTFTDDGNKYITETEFLRKHSPKA 408
           +R ++G   I + +  GF+   PK +     DG K+   +EFLR HSP A
Sbjct: 9   SRRVHGTSFITIPKLSGFSIVSPKQVEVEYADGTKFNFSSEFLRIHSPAA 58


  Database: All non-redundant GenBank CDS
  translations+PDB+SwissProt+PIR+PRF
    Posted date:  Mar 19, 2003 11:08 PM
  Number of letters in database: 441,946,756
  Number of sequences in database:  1,375,764
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 942,842,623
Number of Sequences: 1375764
Number of extensions: 19204060
Number of successful extensions: 51680
Number of sequences better than 10.0: 58
Number of HSP's better than 10.0 without gapping: 48459
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 51594
length of database: 441,946,756
effective HSP length: 126
effective length of database: 268,600,492
effective search space used: 78162743172
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)